| 产品详情 |
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| Product Name | MALT1 Inhibitor, MI-2 |
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| Description | MW: 455.72, Purity ≥98% by HPLC. MALT1 inhibitor MI-2 is a potent inhibitor of the paracaspase MALT1 (Mucosa-associated-lymphoid-tissue lymphoma-translocation gene 1) (IC50 = 5.84 µM). MI-2 binds directly to MALT1 and irreversibly suppresses protease function. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo. |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | MI-2,2-chloro-N-(4-(5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl)phenyl)acetamide |
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| Gene, Accession, CAS # | CAS: 1047953-91-2 |
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| Catalog # | B2368-25 |
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| Order / More Info | MALT1 Inhibitor, MI-2 from BIOVISION, INC. |
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| Product Specific References | n/a |
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