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| Product Name | Active Cathepsin D, Human Recombinant |
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| Description | Cathepsin D is a lysosomal aspartyl protease composed of a protein dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer's plaques. Cathepsin D is produced initially as a pre-pro-enzyme which gets transported to lysosomes via endosomes in most cell types. In endosomes, it gets proteolyzed by unidentified proteases by removal of the pro-peptide to generate active single-chain Cathepsin D; while in lysosomes, further proces |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Procathepsin D, CTSD |
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| Gene, Accession, CAS # | CTSD, Gene ID: 1509, Accession: P07340 |
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| Catalog # | 9229-50 |
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| Order / More Info | Active Cathepsin D, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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