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Product Name | MEG (sulfate) |
Description | MEG is a selective iNOS inhibitor and scavenger of peroxynitrite. The EC50 values for inhibition of iNOS (LPS-treated rat lung), eNOS (bovine endothelial), and nNOS (rat brain) are 11.5, 110, and 60 µM, respectively.{7417} MEG reacts with peroxynitrite with a second order rate constant of 1,900 M−1s−1 at 37°C.{4278} MEG has potent anti-inflammatory activity, which may be due to the combined effect of MEG acting as an inhibitor of iNOS and as a scavenger of peroxynitrite.{5922} |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | iNOS inducible nitric oxide synthases inhibitors peroxynitrite scavenger selective 2-mercaptoethyl-guanidine |
Gene, Accession, CAS # | CAS: 3979-00-8 |
Catalog # | 81020-100 |
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Order / More Info | MEG (sulfate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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