产品名称 Harmine from CAYMAN CHEMICAL COMPANY
产品货号 10010324-250
产品价格 现货询价,电话:010-67529703
产品规格 250 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameHarmine
DescriptionHarmine is a β-carboline alkaloid that was first isolated from seeds of Peganum harmala (Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPARγ expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner.{14921} Administration of harmine (30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression (TNFα, IL-1β, iNOS) and macrophage accumulation in adipose tissue.{14921}
Size250 mg
Concentrationn/a
ApplicationsMass Spectrometry
Other Namesmetabolic syndromes obesity diabetes PPAR.gamma. insulin sensitivity metabolism .beta.-carboline b-carboline alkaloids hyperglycemia signalling pathway inflammatory gene expression endocrinology
Gene, Accession, CAS #CAS: 442-51-3
Catalog #10010324-250
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Order / More InfoHarmine from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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