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| Product Name | Harmine |
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| Description | Harmine is a β-carboline alkaloid that was first isolated from seeds of Peganum harmala (Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPARγ expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner.{14921} Administration of harmine (30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression (TNFα, IL-1β, iNOS) and macrophage accumulation in adipose tissue.{14921} |
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| Size | 1000 mg |
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| Concentration | n/a |
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| Applications | Mass Spectrometry |
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| Other Names | metabolic syndromes obesity diabetes PPAR.gamma. insulin sensitivity metabolism .beta.-carboline b-carboline alkaloids hyperglycemia signalling pathway inflammatory gene expression endocrinology |
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| Gene, Accession, CAS # | CAS: 442-51-3 |
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| Catalog # | 10010324-1 |
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| Order / More Info | Harmine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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