| 产品详情 |
| Edit |   |
|---|
| Product Name | Harmine |
|---|
| Description | Harmine is a β-carboline alkaloid that was first isolated from seeds of Peganum harmala (Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPARγ expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner.{14921} Administration of harmine (30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression (TNFα, IL-1β, iNOS) and macrophage accumulation in adipose tissue.{14921} |
|---|
| Size | 500 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Mass Spectrometry |
|---|
| Other Names | metabolic syndromes obesity diabetes PPAR.gamma. insulin sensitivity metabolism .beta.-carboline b-carboline alkaloids hyperglycemia signalling pathway inflammatory gene expression endocrinology |
|---|
| Gene, Accession, CAS # | CAS: 442-51-3 |
|---|
| Catalog # | 10010324-500 |
|---|
| Price | |
|---|
| Order / More Info | Harmine from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|