| 产品详情 |
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| Antigenic Specificity | AIF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, IHC, WB, IP, IF • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-AIF polyclonal antibody. This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sen |
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| Immunogen | apoptosis-inducing factor, mitochondrion-associated, 1 |
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| Other Names | AIF, AIFM1, PDCD8 |
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| Gene, Accession # | Gene ID: 9131, UniProt: O95831 |
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| Catalog # | FNab00235 |
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| Price | |
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| Order / More Info | AIF Antibody from FINETEST |
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| Product Specific References | n/a |
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