| 产品详情 |
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| Antigenic Specificity | APP?C-Terminal ? |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-APP?C-Terminal ?polyclonal antibody. This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding se |
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| Immunogen | amyloid beta A4 precursor protein |
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| Other Names | A4, ABPP?Alzheimer disease amyloid protein?Cerebral vascular amyloid peptide?Beta-amyloid precursor protein?CVAP?PreA4 |
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| Gene, Accession # | Gene ID: 351, UniProt: P05067 |
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| Catalog # | FNab00512 |
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| Price | |
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| Order / More Info | APP?C-Terminal ? Antibody from FINETEST |
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| Product Specific References | n/a |
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