产品名称 APC Antibody from IMMUQUEST LTD.
产品货号 IQ615HRP
产品价格 现货询价,电话:010-67529703
产品规格 50ul
产品品牌 IMMUQUEST LTD.
产品概述
产品详情
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Antigenic SpecificityAPC
CloneAli 12-28
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatperoxidase (HRP) conjugate
Size50ul
Concentration1mg/ml
ApplicationsELISA, IHC-Fr, IP, WB
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DescriptionMouse anti APC [Ali 12-28]: Horseradish peroxidase (HRP). This antibody recognises adenomatous polyposis coli (APC), a 310kDa protein that functions as a tumour suppressor. APC tumour suppressor gene is mutated in the inherited disease familial adenomatous polyposis (FAP) and in over 80% of colorectal cancers. The antibody Ali 12-28 recognises a region corresponding to nucleotides 135 and 422 of the APC (exons 2-3) in the N-terminus. It detects both normal and mutant-truncated forms of the APC and may be used for the detection of APC expression and APC mutations. Species reactivity: Human. Does not cross react with mouse
ImmunogenN-terminal APC-MBP fusion protein
Other Namesadenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; Adenomatous polyposis coli protein; APC; BTPS2; Deleted in polyposis 2.5; DP2; DP2.5; DP3; GS; Protein APC
Gene, Accession #n/a
Catalog #IQ615HRP
Price
Order / More InfoAPC Antibody from IMMUQUEST LTD.
Product Specific ReferencesEfstathiou JA, et al. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci.1998.95(6):3122-7. PMID:9501226 http://www.ncbi.nlm.nih.gov/pubmed/9501226
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