产品名称 CD11/CD18 Antibody from IMMUQUEST LTD.
产品货号 IQ639FITC
产品价格 现货询价,电话:010-67529703
产品规格 50ul
产品品牌 IMMUQUEST LTD.
产品概述
产品详情
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Antigenic SpecificityCD11/CD18
Clone24
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size50ul
Concentration0.9mg/ml
ApplicationsFlow cyt, ICC/IF
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DescriptionMouse anti CD11/CD18 [24]: Fluorescein. This antibody recognises integrin alpha L,M,X/Beta 2 (CD11/CD18). Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1) with integrin alpha M (CD11b) to form Complement Receptor 3 (CR3) and with integrin alpha X (CD11c) to form Complement Receptor 4 (CR4). Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs). Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
ImmunogenFibronectin-purified human monocytes
Other NamesIntegrin alpha (L, M, X)/beta 2
Gene, Accession #n/a
Catalog #IQ639FITC
Price
Order / More InfoCD11/CD18 Antibody from IMMUQUEST LTD.
Product Specific ReferencesHogg N, et al. An anti-human monocyte/macrophage monoclonal antibody, reacting most strongly with macrophages in lymphoid tissue. Cell Immunol. 1985. 92(2):247-53. PMID:2581704 http://www.ncbi.nlm.nih.gov/pubmed/2581704
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