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| Product Name | A83-01 |
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| Description | MW: 421.5. Purity >98% (TLC); NMR (Conforms). ALK inhibitorSelective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50=104 nM). Inhibits -amyloid-mediated neurodegeneration in hippocampal slices. Antiinflammatory activity. Cell permeable. Active in rodent models.Scientific Background: Potent and selective ALK4, 5 and 7 inhibitor (1,2). IC50 |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [AR-A014418 ; N-[(4-Methoxyphenyl) methyl]-N'-(5-nitro-2-thiazolyl)urea; 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide] |
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| Gene, Accession, CAS # | CAS: 909910-43-6 |
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| Catalog # | MBS515040 |
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| Order / More Info | A83-01 from MYBIOSOURCE INC. |
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| Product Specific References | R Bhat et al. J. Biol. Chem. 2003 278: 45937 SH Ramirez et al. Am. J. Pathol. 2010 176:881 |
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