产品详情 |
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Product Name | A 438079 |
Description | Purity ≥99% (HPLC). A potent, competitive, and selective antagonist of P2X7 purinergic receptor (pIC50 = 6.5nM and 6.9nM for rat and human P2X7 receptor, respectively). Shown to reduce ATP-induced reactive oxygen species formation in MEL cells by about 87% (~10uM) and blocks BzATP-stimulated changes in intracellular calcium concentrations (IC50 = 100 and 300nM at rat and human P2X7 receptors, respectively. Developed by Abbott. Synonyms: 3-((5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine Hydrochloride; P2X7 Purinergic Receptor Antagonist; A 438079; A438079; A-438079 CAS No: 899507-36-9 |
Size | 10mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-((5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine Hydrochloride; P2X7 Purinergic Receptor Antagonist; A 438079; A438079; A-438079 |
Gene, Accession, CAS # | n/a |
Catalog # | 217134 |
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Order / More Info | A 438079 from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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