产品详情 |
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Product Name | Recombinant Human FGF-8 (Animal-Free) |
Description | FGF-8 belongs to the fibroblast growth factor (FGF) family and plays an important role in cell growth, embryogenesis, and tumorigenesis. Four isoforms (a, b, e, and f) of human FGF-8 generated by alternative splicing of the mRNA have been described. The isoforms may have different functions during embryogenesis. During prenatal stages, FGF-8 is required for the normal development of various organs, including limbs and central nervous system. FGF-8 was first cloned from SC-3 mouse mammary carcinoma cells and was found to be induced in response to androgenic stimuli. FGF-8 is found to have a transforming capacity and is detected in human prostate and breast carcinoma specimens and cell lines. The isoform FGF-8b has the highest affinity to FGF receptors and the strongest transforming capacity. |
Size | 25 µg |
Concentration | n/a |
Applications | BA |
Other Names | Fibroblast growth factor 8 (FGF8), Androgen-induced growth factor (AIGF), Heparin-binding growth factor 8 (HBGF-8, HBGF8) |
Gene, Accession, CAS # | Gene ID: 2253 |
Catalog # | 710504 |
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Order / More Info | Recombinant Human FGF-8 (Animal-Free) from BIOLEGEND |
Product Specific References | n/a |
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