| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CBL |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100µg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:100 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit anti-CBL polyclonal antibody. This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in |
|---|
| Immunogen | Cas-Br-M (murine) ecotropic retroviral transforming sequence |
|---|
| Other Names | CBL2, RNF55 |
|---|
| Gene, Accession # | Gene ID: 867, UniProt: P22681 |
|---|
| Catalog # | FNab01317 |
|---|
| Price | |
|---|
| Order / More Info | CBL Antibody from FINETEST |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|