产品详情 |
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Product Name | PF-670462 |
Description | PF-670462 is a potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other kinases. Inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo. MW: 410.32. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride |
Gene, Accession, CAS # | CAS: 950912-80-8 |
Catalog # | B2271-5 |
Price | |
Order / More Info | PF-670462 from BIOVISION, INC. |
Product Specific References | n/a |
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