| 产品详情 |
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| Product Name | PF-3084014 |
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| Description | An inhibitor of γ-secretase (IC50s = 6.2 and 1.2 nM, respectively, in an enzyme assay and in whole cells); does not induce Notch-related toxicity (EC50s = 1,300-3,000 nM for B cells in fetal thymic organ cultures); reduces the level of Aβ40 fragments in mouse brain three hours following 1 to 18 mg/kg doses and the level of Aβ42 fragments levels at 9 or 18 mg/kg; reduces Aβ fragments when at 0.3-3 mg/kg per day for five days |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1290543-63-3 |
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| Catalog # | 27061-10 |
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| Price | |
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| Order / More Info | PF-3084014 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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