| 产品详情 |
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| Antigenic Specificity | SFPQ |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC • WB 1:500 - 1:1000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-SFPQ polyclonal antibody. SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. Catal |
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| Immunogen | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) |
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| Other Names | PSF |
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| Gene, Accession # | Gene ID: 6421, UniProt: P23246 |
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| Catalog # | FNab07785 |
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| Price | |
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| Order / More Info | SFPQ Antibody from FINETEST |
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| Product Specific References | n/a |
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