产品名称 CD55, Mouse Antibody from HYCULT BIOTECH
产品货号 HM1115F
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 HYCULT BIOTECH
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityCD55, Mouse
Clone3D5
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatfluorescein (FITC) conjugate
Size100 µg
Concentration100 µg/ml
ApplicationsFC, immunoassay, paraffin sections, WB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe monoclonal antibody 3D5 recognizes complement decay accelerating factor (DAF), also designated as CD55. Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor, membrane cofactor protein (MCP) and CD59. CR1, CD55 and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, CD55), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Mouse CD55 is a 60 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. CD55 is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although CD55 does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators CD55 protects self-cells from autologous complement-mediated injury. CD55 cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point.
ImmunogenNRK cells expressing transmembrane-anchored mouse DAF
Other NamesComplement decay-accelerating factor, GPI-anchored, DAF-GPI.
Gene, Accession #Cd55, Cd55a, Daf, Daf1
Catalog #HM1115F
Price
Order / More InfoCD55, Mouse Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
产品资料