产品详情 |
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Antigenic Specificity | Lipoteichoic acid |
Clone | 55 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG3 |
Format | unconjugated |
Size | 100 µg |
Concentration | 100 µg/ml |
Applications | frozen sections, FC, immunoassay, IF, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody 55 recognizes lipoteichoic acid (LTA). LTA, a glycerol phosphate surface polymer, is a component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface. |
Immunogen | Microbial mixture of Streptococcus sobrims HG961, HG962, HG970 and HG977 |
Other Names | LTA |
Gene, Accession # | n/a |
Catalog # | HM5018 |
Price | |
Order / More Info | Lipoteichoic acid Antibody from HYCULT BIOTECH |
Product Specific References | n/a |
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