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Product Name | 2-Methoxyestradiol |
Description | Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly. Purity 99%. MW (observed): 302.41 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol |
Gene, Accession, CAS # | CAS: 362-07-2 |
Catalog # | 1807/10 |
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Order / More Info | 2-Methoxyestradiol from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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