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Product Name | Mouse Regulatory B cell (B10) Flow Kit (CD19 FITC/CD5 PE/CD1d Alexa Fluor® 647) |
Description | Splenic IL-10-producing CD1dhighCD5+ B cells have been designated as regulatory B cells (Breg or B10). These rare IL-10- producing B cells represent only 1%-2% of spleen B cells and 7%-8% of peritoneal B cells in mice but are not normally detectable in blood or lymph nodes. B10 cells are a unique subset of potent regulatory B cells different from B-1a, B-1b, or CD21+CD23- mantle zone B cells. B10 cells produce IL-10 and negatively regulate T cell function. BioLegend's Mouse Regulatory B Cell Flow Kit is composed of fluorochrome conjugated anti-mouse CD19, CD5, and CD1d. It is optimized for detection or isolation of B10 cells by flow cytometry. |
Size | 25 tests |
Concentration | Flow Cytometry (FC) |
Applications | n/a |
Other Names | B reg |
Gene, Accession, CAS # | Gene ID: 12478 |
Catalog # | 132601 |
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Order / More Info | Mouse Regulatory B cell (B10) Flow Kit (CD19 FITC/CD5 PE/CD1d Alexa Fluor® 647) from BIOLEGEND |
Product Specific References | n/a |
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