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| Product Name | a1-Antichymotrypsin, Human Plasma |
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| Description | Purity ~95% (SDS-PAGE). Alpha 1 antichymotrypsin is an acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer. Defects in this gene may be a cause of chronic obstructive pulmonary disease. Source: Human Plasma Molecular Weight: ~64kD Biological Activity: Shows 75-100% inhibition when tested with active-site titrated porcine pancreatic trypsin using Na-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | a1-Antichymotrypsin, Human Plasma (Alpha 1 Antichymotrypsin, Cell growth-inhibiting gene 24/25 protein, Serpin A3, SERPINA3, AACT, GIG24, GIG25) |
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| Gene, Accession, CAS # | Gene ID: 12, SwissProt: P01011 |
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| Catalog # | A2255-02 |
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| Order / More Info | a1-Antichymotrypsin, Human Plasma from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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