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Product Name | SP-2509 |
Description | SP-2509 is a reversible inhibitor of Lysine-specific demethylase (LSD1) (IC50 = 13 nM). It has no effect on monoamine oxidases A and B. SP2509 attenuates the binding of LSD1 to CoREST, allowing increased methylation of H3K4 and driving increased expression of p21, p27, and CCAAT/enhancer binding protein α in cultured acute myeloid leukemia (AML) cells. MW: 437.9. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-?(4-?morpholinylsulfonyl)-?benzoic acid (2E)-?2-?[1-?(5-?chloro-?2-?hydroxyphenyl)ethylidene]hydrazide |
Gene, Accession, CAS # | CAS: 1423715-09-6 |
Catalog # | 9446-25 |
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Order / More Info | SP-2509 from BIOVISION, INC. |
Product Specific References | n/a |
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