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| Product Name | Phospho-ERK1/2 (Thr202/Tyr204) Translocation Assay Kit (Cell-Based) |
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| Description | Mitogen-activated protein kinases (MAPKs) are proline-directed serine and threonine protein kinases that regulate numerous physiological cell responses including: embryogenesis, cell differentiation, proliferation, migration, apoptosis and death. Extracellular signal-regulated kinases (ERKs) 1 and 2 (ERK1/2), also known as p44 MAPK and p42 MAPK respectively, belong to one of the five major groups of MAPKs. Closely-related ERK1/2 isoforms are uniquely activated by several extracellular signals including growth factors, cytokines, hormones, and neuro-transmitters. Activation of ERK1/2 by the upstream kinases MEK1 and MEK2 occurs via dual phosphorylation on specific threonine (Thr202) and tyrosine (Tyr204) residues on the T*EY* motif. MEK1 and |
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| Size | 50 assays |
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| Concentration | n/a |
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| Applications | Detection of nuclear translocation of phospo-ERK1 and phospo-ERK2 in mammalian cells |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K696-50 |
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| Order / More Info | Phospho-ERK1/2 (Thr202/Tyr204) Translocation Assay Kit (Cell-Based) from BIOVISION, INC. |
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| Product Specific References | n/a |
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