产品详情 |
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Antigenic Specificity | CBR1 |
Clone | 2C9-B12-C4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | WB, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody to detect CBR1. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
Immunogen | Recombinant human CBR1 protein fragments expressed in E.coli |
Other Names | Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase, Short chain dehydrogenase/reductase family 21C member 1 |
Gene, Accession # | Gene ID: 873, Accession: P16152 |
Catalog # | A1325-100 |
Price | |
Order / More Info | CBR1 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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