| 产品详情 |
| Edit |   |
|---|
| Product Name | Glyoxalase II Activity Kit (Colorimetric) |
|---|
| Description | Glyoxalase II (GloII, hydroxyacylglutathione hydrolase, EC 3.1.2.6) is one of the two enzymes in the Glyoxalase system that is ubiquitously expressed in mammalian, plants and bacteria. The Glyoxalase system is a biological pathway that detoxifies cells by metabolizing α-ketoaldehydes such as methylglyoxal, a cytotoxic byproduct of lipids and glucose metabolism. GloII fulfills the terminal step in the glyoxalase system: It catalyzes the hydrolysis of S-D-lactoyl-glutathione (SLG) to reduced glutathione and D-lactic acid. The alteration of GloII activity in cell growth cycle, cell differentiation, phagocyte activation and diabetes mellitus development of implies this enzyme plays a wide-ranging and important role in cell function and disease progression. Research areas of current interest in Glo-II include diabetes, and cancer therapy. Glyoxalase II Activity Kit utilizes the ability of an active Glo-II to cleave a substrate while producing D-lactate. The produced D-Lactate reacts with the chromophore generating a stable signal that can be easily quantified at 450 nm using a microplate reader. Our assay kit is simple, sensitive and can detect as low as 0.6 mU/ml of Glo-II activity in biological samples. |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | Measurmente of Glyoxalase II activity in biological samples |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | Kit-2337 |
|---|
| Price | |
|---|
| Order / More Info | Glyoxalase II Activity Kit (Colorimetric) from CREATIVE BIOMART |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|