产品名称 ACER1 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-BL180
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityACER1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB, IHC
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DescriptionRabbit Anti-Human ACER1 polyclonal antibody for WB, IHC. Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum;corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can;trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and;sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers;regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at;the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is;highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine;(Houben et al., 2006 (PubMed 16477081); Sun et al., 2008 (PubMed 17713573)).
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 125981, UniProt: Q8TDN7
Catalog #CABT-BL180
Price
Order / More InfoACER1 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料