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Product Name | ICA (Islet Cell Antibody) screen ELISA |
Description | The ICA Screen ELISA Assay Kit system uses the ability of IC autoantibodies to act di-valently, that is, to form a bridge between autoAntigenss (highly purified material from primate source) coated onto the plate and liquid phase autoAntigens-Biotin. In the first step IC autoantibodies from the sample bind to autoAntigenss coated on the microtiter plate. In a second step IC-autoAntigens-Biotin binds to this complex which correlates with the amount of IC autoantibodies in patient's serum. Unbound IC-autoAntigens-Biotin is removed by washing. Sample Types: serum. Range: Cut Off Control. Sensitivity: n/a. Time: overnight • Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), results from a chronic autoimmune process which destructs the insulin-secreting pancreatic beta cells. This is caused by simultaneous action of specific auto-reactive CD4+ and CD8+ T lymphocytes. Even before the onset of type 1 diabetes autoantibodies against different Antigenss of the islet cells can be detected in the serum of those patients. This process may take years to complete and may occur at any time at all ages. |
Size | 1 x 96 well |
Concentration | n/a |
Applications | RUO |
Other Names | ICA, Islet Cell Antibody, Antibodies |
Gene, Accession, CAS # | n/a |
Catalog # | ICA31-K01 |
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Order / More Info | ICA (Islet Cell Antibody) screen ELISA from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |
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