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| Product Name | Total Infliximab (Remicade®) ELISA Assay Kit |
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| Description | he ImmunoGuide Antibody to Infliximab assay is a sandwich type ELISA for the determination of total antibodies (free and Infliximab-bound) against Infliximab in serum and plasma samples. During sample preparation, the Infliximab-bound anti-Infliximab antibodies are separated from the complex in order to acquire free anti-Infliximab antibodies. During the incubation period, antibodies to Infliximab (ATI) are replaced and bridged in the well with its Fab arms, between the Infliximab coated on the well and the conjugated Infliximab labelled with peroxidase. After washing away the components the bound enzymatic activity is detected by addition of tetramethylbenzidine (TMB) chromogen-substrate. Finally, the reaction is terminated with stop solution. The positive reaction is related with the presence of ATI in the sample. The semi-quantitative calculation is made by using the Cut-off control as a reference. Sample Types: serum, plasma. Range: 10 tAU/mL. Sensitivity: Cut-off. Time: 1.5 hours • The drug Infliximab (trade name Remicade® and Remsima®) is a chimeric monoclonal antibody and used to treat auto-immune disorders. One of the major concerns, despite of its wide usage, is the potential development of anti-Infliximab antibodies (ATI) which in turn may interfere with the drug efficacy as mainly judged by observing the relapse of signs and symptoms of disease and necessitate dose-escalation or potentially ending up the treatment.The ImmunoGuide Total Antibody to Infliximab ELISA Kit can be efficiently used for measuring free and Infliximab-bound antibodies against the drug Infliximab. In combination with the drug level determination, the Total Antibody to Infliximab ELISA Kit has been designed for the measurement of free antibodies against this drug. It also detects such antibodies which already are bound to the drug, even if the drug is present in a 20 fold excess. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IG-TA101 anti drug antibody kits shikari shakari free Infliximab Remicade ELISA mAb,Assay Kit EIA, Immunoassay, anti-drug, TR-QS-INF, IG-AB101 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | IG-TA101 |
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| Order / More Info | Total Infliximab (Remicade®) ELISA Assay Kit from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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