产品详情 |
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Antigenic Specificity | ESRP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ESRP2 Polyclonal Antibody. RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition. |
Immunogen | n/a |
Other Names | PP7059, RBM35B; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B; RNA-binding protein 35B |
Gene, Accession # | Entrez: 77411, 80004; Uniprot: Q8K0G8, Q9H6T0 |
Catalog # | PA5-21110 |
Price | |
Order / More Info | ESRP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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