产品详情 |
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Product Name | Crotamiton |
Description | An ectoparasiticide and antipruritic agent; blocks mouse TRPV4 channel expressed in HEK293 cells in a calcium-dependent manner (IC50s = 223.5 and 15.5 µM in buffer containing 0 and 2 mM calcium, respectively); inhibits scratching behavior in mice induced by the TRPV4 agonist GSK1016790A; topical application inhibits scratching behavior in mice induced by histamine, serotonin, and the PAR2 agonist SLIGRL-NH2 (0.025 g of a 10% ointment) |
Size | 25 g |
Concentration | n/a |
Applications | n/a |
Other Names | N-Ethyl-o-Crotonotoluidide |
Gene, Accession, CAS # | CAS: 483-63-6 |
Catalog # | 23943-25 |
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Order / More Info | Crotamiton from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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