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| Product Name | SIRT6 Inhibitor Screening Kit (Fluorometric) |
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| Description | SIRT6 or Sirtuin 6 proteins are a class of proteins that possess either histone deacetylase or mono-ribosyltransferase activity. SIRT6 is a nuclear sirtuin that has been associated with aging, cellular protection, sugar metabolism and certain types of cancer. Broad therapeutic applications are foreseen for SIRT6 inhibitors, including uses in diabetes, immune-mediated disorders, and cancer. Unlike other known protein deacetylases, which simply hydrolyze acetyl-lysine residues, the sirtuin-mediated deacetylation reaction hydrolyzes acetyl-lysine and NAD. This hydrolysis yields the deacetylated substrate, O-acetyl-ADP-ribose and nicotinamide, itself an inhibitor of sirtuin activity. Studies suggest that the human sirtuins may function as intra |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screening/characterizing/studying SIRT6 inhibitors |
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| Other Names | Sirtuin 6 Inhibitor Screening Kit (Fluorometric) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K323-100 |
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| Order / More Info | SIRT6 Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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