产品详情 |
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Antigenic Specificity | LEFTY A |
Clone | 7C5G1H6H10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot. This antibody is suitable for ELISA and western blotting. The antibody may be used for other applications, such as RIA, immunohistochemistry or immunoprecipitation, but specific reaction conditions have not been developed. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This protein A purified mouse monoclonal antibody reacts with a 30 kDa protein corresponding to human LEFTY. No reactivity occurs against 6X HIS tag. Significant sequence homology exists between the human and mouse forms of LEFTY. Cross reactivity is expected with mouse and rat forms of the protein. Reactivity with other sources has not been determined. |
Immunogen | A BALB/c mouse was immunized with a recombinant form of 6X HIS tagged human LEFTY. |
Other Names | mouse anti-leftyA antibody, mouse anti-protein lefty 2 antibody, Left-right determination factor 2 antibody, Protein lefty-2 antibody, Left-right determination factor A antibody, Protein lefty-A antibody, Transforming growth factor beta-4 antibody, TGF-beta-4 antibody, Endometrial bleeding-associated factor antibody |
Gene, Accession # | LEFTY2, Gene ID: 7044, NCBI: NP_001165896.1, UniProt: O00292 |
Catalog # | 200-301-279 |
Price | |
Order / More Info | LEFTY A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | Ulloa, L. and Tabibzadeh, S. (2001) Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. J Biol Chem, 276(24): 21397-404. Meno, R. et al: (1998) Lefty -1 is required for the left-right determination as a regulator of Lefty-2 and Nodal. Cell 94: 287. Tsukui, T., et al. (1999) Multiple left-right asymmetry defects in Shh-/- mutant mice unveil a convergence of the Shh and retinoic acid pathways in the control of Lefty-1. Proc. Natl. Acad. Sci USA 96: 11376-11381. |
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