产品名称 BRM bromodomain TR-FRET Assay Kit from CAYMAN CHEMICAL COMPANY
产品货号 600730-1920WELLS
产品价格 现货询价,电话:010-67529703
产品规格 1920 well
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameBRM bromodomain TR-FRET Assay Kit
DescriptionThe SWI/SNF family of ATP-dependent chromatin remodeling enzymes catalyzes structural changes that allow proteins to access the nucleosomal DNA, alter the position of the nucleosomes on the DNA, or eject the histone octamer from the template. Mammalian SWI/SNF remodelers contain either BRM (SMARCA2) or BRG1 (SMARCA4) as their catalytic subunit. These subunits also contain a C-terminal bromodomain that binds to acetylated residues on histone tails. Small molecule inhibitors of BRM interactions with peptide binding partners hold promise as useful therapeutics for human disease. Cayman's BRM bromodomain TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of inhibitors of bromodomain/acetylated peptide interaction in a high throughput format. This screening assay is robust, displaying a Z' >0.6.
Size1920 well
Concentrationn/a
ApplicationsHigh-Throughput Screening, TR-FRET
Other NamesSMARCA2
Gene, Accession, CAS #n/a
Catalog #600730-1920WELLS
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Order / More InfoBRM bromodomain TR-FRET Assay Kit from CAYMAN CHEMICAL COMPANY
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