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Product Name | Mirtazapine |
Description | Antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo. Purity 99%. MW (observed): 265.36 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine. Org 3770, 6-Azamianserin |
Gene, Accession, CAS # | CAS: 85650-52-8 |
Catalog # | 2018/10 |
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Order / More Info | Mirtazapine from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21966518, 26114334 |
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