产品详情 |
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Product Name | SSR 128129E |
Description | An FGFR inhibitor (IC50 = 1.9 nM); reduces FGF2-induced endothelial cell proliferation and migration (IC50s = 31 and 15.2 nM, respectively); reduces proliferation of cells expressing FGFR1-4 at 100 nM; reduces disease severity and enhances physical performance in a mouse model of arthritis at 30 mg/kg per day; reduces tumor growth and metastasis in a Panc02 mouse orthotopic tumor model; reduces atherosclerotic lesion size in the aortic sinus of apoE-/- mice at 50 mg/kg per day; reduces intimal hyperplasia following jugular vein-to-artery bypass grafting surgery in rats, |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 848463-13-8 SSR128129E SSR-128,129E FGF-2 FGFR-1 2 3 4 hB-9α VEGFR-2 mPanc-02 anti-tumor Panc fibroblast growth factor |
Gene, Accession, CAS # | CAS: 848318-25-2 |
Catalog # | 22128-25 |
Price | |
Order / More Info | SSR 128129E from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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