| 产品详情 |
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| Product Name | Icatibant (acetate) |
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| Description | A synthetic peptide antagonist of the bradykinin B2 receptor (IC50 = 1.07 nM; Ki = 0.798 nM); inhibits bradykinin-induced contractions in isolated guinea pig ileum and pulmonary arteries as well as in rat uterus (IC50s = 11, 5.4, and 4.9 nM, respectively); inhibits bradykinin-induced bronchoconstriction in a guinea pig model (ID50s = 13.4 and 31.8 pmol/kg, i.v., for pulmonary resistance and dynamic lung compliance, respectively); reduces vascular permeability in a mouse model of hereditary angioedema (30 µg, i.v.) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HOE 140 |
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| Gene, Accession, CAS # | CAS: 138614-30-9 |
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| Catalog # | 24083-5 |
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| Price | |
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| Order / More Info | Icatibant (acetate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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