产品详情 |
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Product Name | CO-1686 |
Description | An irreversible inhibitor of mutant forms of EGFR including T790M (Ki = 21.5 nM) with minimal activity at the wild-type EGFR (Ki = 303.3 nM); inhibits the proliferation of NSCLC cells expressing mutant EGFR (GI50s = 7-32 nM) and demonstrates anti-tumor activity in NSCLC EGFR mutant xenograft and transgenic models |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AVL-301 |
Gene, Accession, CAS # | CAS: 1374640-70-6 |
Catalog # | 16244-1 |
Price | |
Order / More Info | CO-1686 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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