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| Product Name | Lck, Active |
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| Description | Lck (p56lck) is a member of the src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and overexpressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene. Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show overexpression of Lck, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers. Colon cancers and T-cell leukemias frequently show defective regulation of Lck expression and activity.Inappropriate T cell activation and proliferation have been identified as an early event in auto-immu |
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| Size | 5 µg |
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| Concentration | 5µg/50 µl |
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| Applications | RUO |
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| Other Names | Lck (or leukocyte-specific protein tyrosine kinase), Leukocyte C-terminal Src kinase, Short name=LSK, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase, p56-LCK |
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| Gene, Accession, CAS # | LCK, Gene ID: 3932, Accession: P06239 |
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| Catalog # | 7733-5 |
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| Order / More Info | Lck, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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