| 产品详情 |
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| Product Name | Akt1, Active |
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| Description | Akt1 or Protein Kinase B α(PKBα) is a serine/threonine kinase that belongs to the Akt family. Akt1 is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility (1). The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of Akt1 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1) (2) and phosphoinositide-dependent kinase-2 (possibly ILK) (3). Akt1 has numerous cellular substrates including proteins, which promote the inhibition o |
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| Size | 100 µg |
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| Concentration | 5 µg/50 µl |
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| Applications | RUO |
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| Other Names | Akt, RAC-alpha serine/threonine-protein kinase |
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| Gene, Accession, CAS # | AKT1, Gene ID: 207, Accession: P31749 |
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| Catalog # | 7701-100 |
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| Order / More Info | Akt1, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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