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Product Name | BMP-11/GDF-11, human recombinant |
Description | GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino acid sequence identity. MW: 25 kDa. Purity ≥98% |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Growth/Differentiation Factor-11, BMP-11 |
Gene, Accession, CAS # | GDF11, Gene ID: 10220, Accession: O95390 |
Catalog # | 7155-50 |
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Order / More Info | BMP-11/GDF-11, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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