产品名称 EXP-3174 from BIOVISION, INC.
产品货号 9672-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 BIOVISION, INC.
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Product NameEXP-3174
DescriptionEXP-3174 is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. EXP-3174 is a potent angiotensin II receptor, type 1 (AT1) antagonist (Kis = 0.57 and 0.67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of action than losartan. However, the metabolite has very low oral bioavailability. MW: 436.9. Purity ≥98% by HPLC
Size5 mg
Concentrationn/a
Applicationsn/a
Other Names1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid; Losartan carboxylic acid
Gene, Accession, CAS #CAS: 124750-92-1
Catalog #9672-5
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