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| Antigenic Specificity | CD366 (Tim-3) |
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| Clone | B8.2C12 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | PerCP-Cyanine5.5 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PerCP/Cyanine5.5 anti-mouse CD366 (Tim-3). CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
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| Immunogen | mTim-3 protein/Freund adjuvant |
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| Other Names | T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366 |
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| Gene, Accession # | Gene ID: 171285 |
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| Catalog # | 134011 |
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| Price | |
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| Order / More Info | CD366 (Tim-3) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21276089 |
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