产品详情 |
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Antigenic Specificity | CD366 (Tim-3) |
Clone | F38-2E2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD366 (Tim-3). CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
Immunogen | Human Tim-3 fusion protein |
Other Names | T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366 |
Gene, Accession # | Gene ID: 84868 |
Catalog # | 345002 |
Price | |
Order / More Info | CD366 (Tim-3) Antibody from BIOLEGEND |
Product Specific References | n/a |
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