产品详情 |
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Antigenic Specificity | CD366 (Tim-3) |
Clone | RMT3-23 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD366 (Tim-3). CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
Immunogen | n/a |
Other Names | T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2, CD366 |
Gene, Accession # | Gene ID: 171285 |
Catalog # | 119701 |
Price | |
Order / More Info | CD366 (Tim-3) Antibody from BIOLEGEND |
Product Specific References | n/a |
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