产品名称 RUSC1 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-20822
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityRUSC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsWestern Blot: 1 µg/mL
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DescriptionRUSC1 Polyclonal Antibody. RUSC1, also known as NESCA, shares with the related protein RUSC2 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells. RUSC1 has also been shown to interact with Ikappa-B kinase- (IKK-) -gamma, the regulatory subunit of the IKK complex that is required for NF-kappa-B activation in many signaling pathways such as TNF-R or the TLR pathways. RUSC1 can also bind to the E3 ubiquitin ligase TRAF6, which then catalyzes RUSC1 polyubiquitination. Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma,
Immunogenn/a
Other NamesRP11-21N7.4, NESCA; RUN and SH3 domain-containing protein 1; new molecule containing SH3 at the carboxy-terminus
Gene, Accession #Entrez: 100360417, 23623, 72296; Uniprot: Q8BG26, Q9BVN2
Catalog #PA5-20822
Price
Order / More InfoRUSC1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料