| 产品详情 |
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| Product Name | CCT-251545 |
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| Description | Purity ≥98% by HPLC. MW: 421.93. CCT-251545 is a potent Wnt signaling inhibitor (IC50 = 5 nM). It is a selective inhibitor of the human mediator complex-associated protein kinases Cdk8 and Cdk19. Through its effects on Cdk8 and Cdk19, CCT-251545 alters Wnt pathway-regulated gene expression. CCT-251545 demonstrates weak inhibition of tankyrase enzymes (TNKS1 IC50 > 10 µM, TNKS2 IC50 = 15.0 ± 0 µM). |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CCT251545; 8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one |
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| Gene, Accession, CAS # | CAS: 1661839-45-7 |
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| Catalog # | B2501-5 |
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| Price | |
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| Order / More Info | CCT-251545 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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