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| Product Name | Ahcy, 1-432aa, Mouse, His-tag, E.coli |
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| Description | Purity: > 90% by SDS-PAGE Format: Liquid. In 20mM Tris-Hcl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT. Ahcy, also known as Adenosylhomocysteinase, is an enzyme that catalyzes the reversible hydrolysis of S-sdenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AdoHcy hydrolysis is a reversible reaction with an equilibrium favoring AdoHcy formation, but hydrolysis prevails under physiological conditions due to the rapid removal of adenosine and homocysteine. Thus, AHCY s activity in mammals is directly related to homocysteine level, an independent risk factor for vascular disease. It also functions as a regulator of biological transmethylation by controlling the concentration of AdoHcy, a potent competitive inhibitor of all S-adenosyl-L-methionine methyltransferases. Recombinant mouse Ahcy, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Adenosylhomocysteinase, AA987153, AL024110, CuBP, SAHH |
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| Gene, Accession, CAS # | NP 057870 |
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| Catalog # | ATGP3650 |
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| Order / More Info | Ahcy, 1-432aa, Mouse, His-tag, E.coli from ATGen |
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| Product Specific References | n/a |
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