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Product Name | ZFAND5, 1-213aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Phosphate buffer saline (pH 8.0) containing 30% glycerol, 1mM DTT . ZFAND5 is involved in protein degradation via the ubiquitin-proteasome system. This protein may act by anchoring ubiquitinated proteins to the proteasome and plays a role in ubiquitin-mediated protein degradation during muscle atrophy. ZFAND5 plays a role in the regulation of NF-kappa-B activation and apoptosis and inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. It inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Recombinant human ZFAND5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | AN1-type zinc finger protein 5, AN1-type zinc finger protein 5, ZA20D2, ZFAND5A, ZNF216 |
Gene, Accession, CAS # | NP 005998 |
Catalog # | ATGP2931 |
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Order / More Info | ZFAND5, 1-213aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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