产品详情 |
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Antigenic Specificity | GAD2 |
Clone | CBLG1-480 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | IHC, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-GAD2 Recombinant Antibody (CBLG1-480). This product is antibody recognizes GAD2. The antibody CBLG1-480 immunoassay techniques such as: IHC, IP, WB. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [pr |
Immunogen | Synthetic peptide corresponding to aa4-22, PGSGFWSFGSEDGSGDSEN from within the N-terminal region of human GAD65 conjugated at KLH. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan (100%), Gibbon, Galago, Rat, Ferret, Panda, Bovine, Feline, Canine, Equine, Porcine (95%),Monkey, Marmoset, Mouse, Rabbit, Opossum, Guinea Porcine (89%) |
Other Names | Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain; 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65; |
Gene, Accession # | Gene ID: 2572, UniProt: Q05329 |
Catalog # | CBMAB-G1753-LY |
Price | |
Order / More Info | GAD2 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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